1c (X = trifluoromethanesulfonate, n = 0) crystallizes in a radically different fashion as a consequence of nucleobase rotation about the Pt−N bond, leading to a reversed Hoogsteen arrangement without any intracomplex H bonding between the two bases. This feature essentially corresponds to the solution structure previously proposed by us on the basis of 1H NMR and ESI-MS, with a H-bonding interaction between the aromatic H5‘ proton of 1-MeC and the deprotonated N1 position of 9-EtG. 1b (X = picrate, n = 1) crystallizes to produce a dimetalated base quartet, held together by H-bonding interactions between pairs of cations. nH 2O ( 1) with 9-EtG = 9-ethylguaninate and 1-MeC = 1-methylcytosine are reported. The X-ray crystal structures of two complexes of the composition trans-X
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